BDBM50074893 2-[4-(6,7-Diethoxy-2,3-bis-hydroxymethyl-naphthalen-1-yl)-pyridin-2-yl]-4-pyridin-3-yl-2H-phthalazin-1-one; hydrochloride::CHEMBL557593::T-2585.HCl

SMILES CCOc1cc2cc(CO)c(CO)c(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OCC

InChI Key InChIKey=OEZADIAHVKNQKD-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50074893   

TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50074893(2-[4-(6,7-Diethoxy-2,3-bis-hydroxymethyl-naphthale...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant FLAG-tagged PDE7A expressed in African green monkey COS7 cells using [3H]cAMP as substrate after 30 mins by scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed