BDBM50074898 2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-yl)-pyridin-2-yl]-4-pyridin-3-yl-2H-phthalazin-1-one; hydrochloride::CHEMBL543016

SMILES COc1cc2cc(CO)cc(-c3ccnc(c3)-n3nc(-c4cccnc4)c4ccccc4c3=O)c2cc1OC

InChI Key InChIKey=PVROZLBFLOWVPM-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50074898   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)
Affinity DataKi:  3nMAssay Description:Inhibition of rolipram binding to phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of Phosphodiesterase 4 from guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)
Affinity DataIC50:  81nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50074898(2-[4-(3-Hydroxymethyl-6,7-dimethoxy-naphthalen-1-y...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Phosphodiesterase 5 of guinea pig lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed