BDBM50075177 (E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)-1-(5-methyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-yl)-ethyl]-amide::CHEMBL141684

SMILES C[C@H](NC(=O)\C=C\C(=O)c1cccc(c1)C#N)c1nc2scc(C)c2c(=O)o1

InChI Key InChIKey=AVOPNJYFZROGTB-SYTKJHMZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075177   

TargetGenome polyprotein(Human rhinovirus B)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075177((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...)
Affinity DataIC50:  410nMAssay Description:Inhibitory activity of the compound against varicella zoster virus (VZV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075177((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against cytomegalovirus protease (CMV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 2 (strain HG52) (HHV-2) (Human h...)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075177((E)-4-(3-Cyano-phenyl)-4-oxo-but-2-enoic acid [(S)...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against herpes simplex virus protease (HSV-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed