BDBM50075529 2-(3,5-Di-tert-butyl-4-methoxy-phenyl)-5-methylsulfanyl-[1,3,4]thiadiazole::CHEMBL280326

SMILES COc1c(cc(cc1C(C)(C)C)-c1nnc(SC)s1)C(C)(C)C

InChI Key InChIKey=MPSSPWJTHOFOCH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075529   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075529(2-(3,5-Di-tert-butyl-4-methoxy-phenyl)-5-methylsul...)
Affinity DataIC50:  5.80E+3nMAssay Description:IC50 value against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075529(2-(3,5-Di-tert-butyl-4-methoxy-phenyl)-5-methylsul...)
Affinity DataIC50:  12nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075529(2-(3,5-Di-tert-butyl-4-methoxy-phenyl)-5-methylsul...)
Affinity DataIC50:  340nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50075529(2-(3,5-Di-tert-butyl-4-methoxy-phenyl)-5-methylsul...)
Affinity DataIC50:  770nMAssay Description:IC50 value against Prostaglandin G/H synthase 1 of human platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed