BDBM50075669 2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL23245

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1cccc(F)c1

InChI Key InChIKey=ZQRHHQIODRUYCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075669   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075669(2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50:  6.60E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075669(2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50:  340nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075669(2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-c...)
Affinity DataIC50:  14nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed