BDBM50075750 5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL345863

SMILES CCOC(=O)c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key InChIKey=YXILDSPXTJTSFQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50075750   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075750(5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...)
Affinity DataIC50:  400nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075750(5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...)
Affinity DataIC50:  500nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075750(5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...)
Affinity DataIC50:  90nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075750(5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...)
Affinity DataIC50: >3.00E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075750(5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed