BDBM50075775 4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL351772

SMILES CCCOc1ccc(Br)cc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1

InChI Key InChIKey=HHBOWXZOLYQFNY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50075775   

TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  37nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  7nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  7nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  1.44E+3nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075775(4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...)
Affinity DataIC50:  250nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed