BDBM50076688 CHEMBL266473::trans-7-Ethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

SMILES CCC1CCc2cc3c(cc(=O)oc3cc2N1)C(F)(F)F

InChI Key InChIKey=YNKWXKPDLGJQBC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076688   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076688(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076688(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)
Affinity DataIC50: >10nMAssay Description:In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076688(CHEMBL266473 | trans-7-Ethyl-4-trifluoromethyl-5,6...)
Affinity DataEC50:  7nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed