BDBM50076696 CHEMBL6721::trans-5,7-Diethyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8-aza-anthracen-2-one

SMILES CCC1CC(CC)c2cc3c(cc(=O)oc3cc2N1)C(F)(F)F

InChI Key InChIKey=FWJAPKPHDLQMKB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076696   

TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076696(CHEMBL6721 | trans-5,7-Diethyl-4-trifluoromethyl-5...)
Affinity DataIC50:  7nMAssay Description:In vitro binding affinity at human androgen receptor transfected into COS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076696(CHEMBL6721 | trans-5,7-Diethyl-4-trifluoromethyl-5...)
Affinity DataEC50:  26nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076696(CHEMBL6721 | trans-5,7-Diethyl-4-trifluoromethyl-5...)
Affinity DataIC50: >10nMAssay Description:In vitro antagonistic activity against human androgen receptor using cotransfection assay in CV-1 cells; Not active.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed