BDBM50076791 CHEMBL10990::Lithium; (S)-4-methylsulfanyl-2-{[2'-methyl-5-(5-p-tolyl-furan-2-ylmethoxymethyl)-biphenyl-2-carbonyl]-amino}-butyrate
SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccc(C)cc2)cc1-c1ccccc1C)C([O-])=O
InChI Key InChIKey=KPLVUGOBZAXWSW-LJAQVGFWSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50076791
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair