BDBM50076810 CHEMBL428001::Lithium; (S)-4-methylsulfanyl-2-({2'-methyl-5-[5-(4-trifluoromethyl-phenyl)-furan-2-ylmethoxymethyl]-biphenyl-2-carbonyl}-amino)-butyrate
SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccc(cc2)C(F)(F)F)cc1-c1ccccc1C)C([O-])=O
InChI Key InChIKey=AVEYRMOKDFXVLL-NDEPHWFRSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50076810
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair