BDBM50076811 CHEMBL10877::Lithium; (S)-2-({5-[5-(4-chloro-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate

SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccc(Cl)cc2)cc1-c1ccccc1C)C([O-])=O

InChI Key InChIKey=XWZNGPIAPMKVOC-NDEPHWFRSA-M

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076811   

LigandPNGBDBM50076811(CHEMBL10877 | Lithium; (S)-2-({5-[5-(4-chloro-phen...)
Affinity DataEC50:  0.100nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076811(CHEMBL10877 | Lithium; (S)-2-({5-[5-(4-chloro-phen...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed