BDBM50076812 (S)-2-[(5-{[(Furan-2-ylmethyl)-amino]-methyl}-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid::CHEMBL10572

SMILES CSCC[C@H](NC(=O)c1ccc(CNCc2ccco2)cc1-c1ccccc1)C(O)=O

InChI Key InChIKey=XVGJOWOIPGNNTR-QFIPXVFZSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076812   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50076812((S)-2-[(5-{[(Furan-2-ylmethyl)-amino]-methyl}-biph...)Copy SMILESCopy InChI

Affinity DataIC50:  560nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails ArticlePubMed
Copy BDB DOI