BDBM50077563 CHEMBL64420::[2-(3-Chloro-1H-indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine

SMILES Clc1c[nH]c2cccc(OCCNCCCCc3ccccc3)c12

InChI Key InChIKey=MYZONUPBZFDODL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077563   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077563(CHEMBL64420 | [2-(3-Chloro-1H-indol-4-yloxy)-ethyl...)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A r receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077563(CHEMBL64420 | [2-(3-Chloro-1H-indol-4-yloxy)-ethyl...)
Affinity DataKi:  4.80nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077563(CHEMBL64420 | [2-(3-Chloro-1H-indol-4-yloxy)-ethyl...)
Affinity DataKi:  16nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed