BDBM50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752
SMILES O=C1Cc2c(N1)cccc2OCCNCc1ccccc1
InChI Key InChIKey=CVWQKEFTSSJDLS-UHFFFAOYSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50077578
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D3 in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Inihibition of [3H]-spiperone binding to human Dopamine receptor D2 in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodiumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 306nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenatesMore data for this Ligand-Target Pair