BDBM50077689 (3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine::(3R,4R)-4-{4-[3-(BENZYLOXY)PROPOXY]PHENYL}-3-(2-NAPHTHYLMETHOXY)PIPERIDINE::CHEMBL31466

SMILES C(COCc1ccccc1)COc1ccc(cc1)[C@H]1CCNC[C@@H]1OCc1ccc2ccccc2c1

InChI Key InChIKey=SBQHXMHGXWOGFR-ZWXJPIIXSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50077689   

TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed