BDBM50077693 (3'R,4'R)-3'-(1,4-Dimethoxy-naphthalen-2-ylmethoxy)-6-[3-(2-methoxy-benzyloxy)-propoxy]-1',2',3',4',5',6'-hexahydro-[3,4']bipyridinyl::CHEMBL285146

SMILES COc1ccccc1COCCCOc1ccc(cn1)[C@H]1CCNC[C@@H]1OCc1cc(OC)c2ccccc2c1OC

InChI Key InChIKey=YNZOWKPPAKUTGP-ZUKKLESISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077693   

TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077693((3'R,4'R)-3'-(1,4-Dimethoxy-naphthalen-2-ylmethoxy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077693((3'R,4'R)-3'-(1,4-Dimethoxy-naphthalen-2-ylmethoxy...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed