BDBM50077702 4-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5-(naphthalen-2-ylmethoxy)-piperidin-3-ylmethylsulfanyl]-pyridine::CHEMBL286413

SMILES C(COCc1ccccc1)COc1ccc(cc1)[C@H]1[C@H](CSc2ccncc2)CNC[C@@H]1OCc1ccc2ccccc2c1

InChI Key InChIKey=CKFYLSMACGXFQB-XHFCRVKJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077702   

TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077702(4-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077702(4-[(3S,4R,5R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-5...)
Affinity DataIC50:  490nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed