BDBM50077893 CHEMBL3417069::US9611229, 40
SMILES Fc1ccc(Cn2cc(NCCN3CCC(F)(F)CC3)nn2)cc1F
InChI Key InChIKey=HQMAGSAVQJZZDZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50077893
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
Laboratorios Del Dr. Esteve
US Patent
Laboratorios Del Dr. Esteve
US Patent
Affinity DataKi: 45.5nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Esteve
Curated by ChEMBL
Esteve
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair