BDBM50078167 CHEMBL69064

SMILES [#8]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7](-[#6]-[#6]\[#6]=[#6]-2\c3ccccc3-c3ccccc-23)-[#6]-1

InChI Key InChIKey=SJJUKGVRGZOKFH-MRXNPFEDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078167   

TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50078167(CHEMBL69064)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of rat brain synaptosomes GAT1 assessed as inhibition of [3H]GABA uptake by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rattus norvegicus)
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50078167(CHEMBL69064)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of mouse GAT1 expressed in human HEK293 cell line assessed as inhibition of [3H]GABA uptake measured after 40 mins by LC-ESI-MS/MS analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Rattus norvegicus)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50078167(CHEMBL69064)
Affinity DataIC50:  2.02E+3nMAssay Description:In vitro inhibition of [3H]GABA uptake in rat synaptosomes was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed