BDBM50078356 CHEMBL3414725
SMILES [H][C@@]12CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C)[C@@]([H])(C1)C(=O)N[C@@H](Cc1cccc3ccccc13)C(=O)N[C@@H](Cc1ccc(OCc3cn(nn3)[C@]3([H])CN(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C)[C@@]([H])(C3)C(=O)N[C@@H](Cc3cccc4ccccc34)C(=O)N[C@@H](Cc3ccc(OCc4cn2nn4)cc3)C(O)=O)cc1)C(O)=O
InChI Key InChIKey=BUUIRUGUZNCDSQ-KCUAZDICSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50078356
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Ensemble Therapeutics
Curated by ChEMBL
Ensemble Therapeutics
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of cIAP1 BIR3 (154 to 352 residues) (unknown origin) by fluoresceinated dimeric SMAC peptide based fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Ensemble Therapeutics
Curated by ChEMBL
Ensemble Therapeutics
Curated by ChEMBL
Affinity DataEC50: 34nMAssay Description:Inhibition of XIAP BIR2-3 (124 to 356 residues) C202A/C213G mutant (unknown origin) in human THP1 cells using fluoresceinated caspase-3 substrate by ...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Ensemble Therapeutics
Curated by ChEMBL
Ensemble Therapeutics
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of XIAP BIR3 (241 to 356 residues) (unknown origin) incubated for 60 mins by fluoresceinated modified SMAC peptide based fluorescence pola...More data for this Ligand-Target Pair