BDBM50078568 (S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isobutyl-amino]-N-hydroxy-butyramide::CHEMBL47414

SMILES CC(C)CN([C@@H](CCSCc1ccccc1)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=MVTUAPMXVXQWFM-SANMLTNESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078568   

TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  90nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed