BDBM50078852 CHEMBL221598

SMILES CCCCCCCCC1=C(O)C(=O)C=C(O)C1=O

InChI Key InChIKey=FQAUQBOULILEAV-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078852   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataIC50:  380nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human GPR84 expressed in HEK293 cells assessed as reduction in forskolin-stimulated cAMP production incubated for 60 mins by HTRF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-expressed gene 1 protein(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Naples

Curated by ChEMBL
LigandPNGBDBM50078852(CHEMBL221598)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed