BDBM50078888 CHEMBL3416359

SMILES CCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O

InChI Key InChIKey=ROJYDZSFBXLWIR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078888   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 29nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage-expressed gene 1 protein(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078888(CHEMBL3416359)
Affinity DataIC50: 29nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed