BDBM50079057 4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-benzene-1,3-disulfonic acid diamide::BDBM50222616::CHEMBL88519

SMILES NS(=O)(=O)c1cc(c(cc1Cl)N1C(=O)c2cccnc2C1=O)S(N)(=O)=O

InChI Key InChIKey=HYAWAADXAWDZTP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50079057   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  9nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II (hCA II,cytosolic form).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase II (CAII)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  60nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CAIV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against bovine lung microsomes carbonic anhydrase isozyme IV (bCA IV).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase I (CAI)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
A.P.S. University

Curated by ChEMBL
LigandPNGBDBM50079057(4-Chloro-6-(5,7-dioxo-5,7-dihydro-pyrrolo[3,4-b]py...)
Affinity DataKi:  600nMAssay Description:Inhibition of human cloned Carbonic anhydrase I (hCA I,cytosolic form)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed