BDBM50079428 3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL418992

SMILES Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(Cl)cc2)(c2ccccc2)c2ccccc2)n1

InChI Key InChIKey=PMUCOFCFESYTCH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079428   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079428(3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyr...)
Affinity DataKi:  19.8nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079428(3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyr...)
Affinity DataKi:  94.1nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed