BDBM50079620 CHEMBL3414775

SMILES COC(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O

InChI Key InChIKey=KXULAXICDCSUDZ-WAYWQWQTSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50079620   

TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  1.74E+3nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  759nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  800nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50079620(CHEMBL3414775)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed