BDBM50079792 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-butylphenoxy)-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid with di( TFA)::CHEMBL307974

SMILES CCCCc1ccc(O[C@H]2C[C@H](N(C\C=C\[C@@H](N)CS)C2)C(=O)N[C@@H](CCSC)C(O)=O)cc1

InChI Key InChIKey=LGUQFZZRDNTAAI-UZZQCTRBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079792   

LigandPNGBDBM50079792(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-b...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079792(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-b...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed