BDBM50079792 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-butylphenoxy)-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid with di( TFA)::CHEMBL307974
SMILES CCCCc1ccc(O[C@H]2C[C@H](N(C\C=C\[C@@H](N)CS)C2)C(=O)N[C@@H](CCSC)C(O)=O)cc1
InChI Key InChIKey=LGUQFZZRDNTAAI-UZZQCTRBSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50079792
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair