BDBM50079807 CHEMBL294277::methyl 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-trifluoromethylphenoxy)-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoate with di( TFA)
SMILES COC(=O)[C@H](CCSC)NC(=O)[C@@H]1C[C@@H](CN1C\C=C\[C@@H](N)CS)Oc1ccc(cc1)C(F)(F)F
InChI Key InChIKey=XIXIMCSQSWKBPM-NSZAIORKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50079807
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mus musculus)
Eisai Research Institute
Curated by ChEMBL
Eisai Research Institute
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair