BDBM50081234 3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodecatriene 1-diphosphate (3-vFPP)::3-substituted farnesyl diphosphate analogue

SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]=[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key InChIKey=VLCGYUMYXVRSKX-NCZFFCEISA-K

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081234   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  173nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  173nMAssay Description:Inhibitory activity against recombinant mammalian protein Farnesyltransferase expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed