BDBM50081554 CHEMBL3422067

SMILES O=C(NCC1(CCCCC1)N1CCOCC1)c1ccc2[nH]nc(-c3ccc(cc3)N3CCOCC3)c2c1

InChI Key InChIKey=WROHCHCGJIWAPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081554   

TargetAurora kinase A(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081554(CHEMBL3422067)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of recombinant AURKA (unknown origin) preincubated for 15 mins prior to ATP addition by FRET-based homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081554(CHEMBL3422067)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate preincubated for 15 mins prior to ATP addition by ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Entremed

Curated by ChEMBL
LigandPNGBDBM50081554(CHEMBL3422067)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) preincubated for 15 mins prior to ATP addition by FRET-based homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed