BDBM50081568 6-Methyl-2-(5-methyl-thiophen-2-yl)-1H-[1,8]naphthyridin-4-one::CHEMBL51083

SMILES Cc1ccc(s1)-c1cc(O)c2cc(C)cnc2n1

InChI Key InChIKey=DHZVQTGOVGYXSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081568   

TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081568(6-Methyl-2-(5-methyl-thiophen-2-yl)-1H-[1,8]naphth...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of tubulin polymerization (ITP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Pig)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081568(6-Methyl-2-(5-methyl-thiophen-2-yl)-1H-[1,8]naphth...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed