BDBM50081585 CHEMBL100659::N*4*,N*4*-Dibenzyl-6-(4-methoxy-phenyl)-pteridine-2,4-diamine

SMILES COc1ccc(cc1)-c1cnc2nc(N)nc(N(Cc3ccccc3)Cc3ccccc3)c2n1

InChI Key InChIKey=GFOZGTWUCAGSEA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081585   

TargetNitric oxide synthase, endothelial(Sus scrofa)
Julius-Maximilians University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50081585(CHEMBL100659 | N*4*,N*4*-Dibenzyl-6-(4-methoxy-phe...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against Nitric oxide synthase (derived from porcine brain cerebellum)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50081585(CHEMBL100659 | N*4*,N*4*-Dibenzyl-6-(4-methoxy-phe...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (NOS-I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50081585(CHEMBL100659 | N*4*,N*4*-Dibenzyl-6-(4-methoxy-phe...)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-III with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50081585(CHEMBL100659 | N*4*,N*4*-Dibenzyl-6-(4-methoxy-phe...)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibitory activity against human Nitric oxide synthase-II with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50081585(CHEMBL100659 | N*4*,N*4*-Dibenzyl-6-(4-methoxy-phe...)
Affinity DataIC50:  3.47E+4nMAssay Description:Inhibitory activity against human Nitric oxide synthase-I with 2 uM H4Bip for 30 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed