BDBM50081915 5-[3-(Tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine-2,4-diamine::CHEMBL344592

SMILES Nc1ncc(Cc2cccc(OC3CCCCO3)c2)c(N)n1

InChI Key InChIKey=CRNNZXXXIAOSKP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50081915   

TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081915(5-[3-(Tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine...)
Affinity DataKi:  13nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081915(5-[3-(Tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine...)
Affinity DataKi:  93nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Leishmania major.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081915(5-[3-(Tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine...)
Affinity DataKi:  360nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from Trypanosoma cruzi.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50081915(5-[3-(Tetrahydro-pyran-2-yloxy)-benzyl]-pyrimidine...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of recombinant Dihydrofolate reductase from humans.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed