BDBM50082279 CHEMBL3421767

SMILES [O-][N+](=O)c1ccc(c(OCCCc2ccccc2)c1)-c1cccnc1

InChI Key InChIKey=FYPJWRPXWJDUJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082279   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50082279(CHEMBL3421767)
Affinity DataIC50:  6nMAssay Description:Inhibition of human CYP11B1 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 25 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50082279(CHEMBL3421767)
Affinity DataIC50:  2.08E+3nMAssay Description:Inhibition of rat CYP11B1 expressed in hamster fibroblast using 500 nM [3H]-11-deoxycorticosterone as substrate after 7 hrs by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50082279(CHEMBL3421767)
Affinity DataIC50:  137nMAssay Description:Inhibition of human CYP19 expressed in hamster fibroblast using 500 nM [1beta-3H] androstenedione as substrate by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50082279(CHEMBL3421767)
Affinity DataIC50:  15nMAssay Description:Inhibition of human CYP11B2 expressed in hamster fibroblast using 100 nM [3H]-11-deoxycorticosterone as substrate after 45 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed