BDBM50082425 1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea::1-(3-chlorophenyl)-3-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)urea::CHEMBL141154

SMILES CCn1cc2c(n1)nc(NC(=O)Nc1cccc(Cl)c1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=NWAXVCISHHAARQ-UHFFFAOYSA-N

Data  20 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50082425   

TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataKi:  185nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]-SCH- 58261 from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50082425(1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyr...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration as antagonistic activity against cAMP generation inhibited by IB-MECA in CHO cell membranes transfected with human Adenosine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed