BDBM50082537 (S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL141080

SMILES COc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=ULILDPSFFUSXJH-LBPRGKRZSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50082537   

TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity against truncated collagenase-1 (matrix metalloprotease-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against matrilysin (matrix metalloprotease-7).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against collagenase-3 (matrix metalloprotease-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of neutrophil collagenase (Matrix metalloprotease-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of gelatinase-B (Matrix metalloprotease-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50082537((S)-4-(4-Methoxy-benzenesulfonyl)-2,2-dimethyl-thi...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed