BDBM50082789 4-(3-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phenyl-piperidin-1-yl)-propylcarbamoyl]-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL356978

SMILES COC(=O)C1=C(C)NC(=O)N(C1c1cccc(F)c1)C(=O)NCCCN1CCC(CC1)(C(=O)OC)c1ccccc1

InChI Key InChIKey=RFEHYTXXQXNSOO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082789   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082789(4-(3-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against Alpha-1A adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082789(4-(3-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)
Affinity DataKi:  67nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082789(4-(3-Fluoro-phenyl)-3-[3-(4-methoxycarbonyl-4-phen...)
Affinity DataKi:  150nMAssay Description:In vitro binding affinity against Alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed