BDBM50082808 4-(3,4-Difluoro-phenyl)-6-methoxymethyl-3-[3-(4-methyl-4-phenyl-piperidin-1-yl)-propylcarbamoyl]-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL142243

SMILES COCC1=C(C(N(C(=O)NCCCN2CCC(C)(CC2)c2ccccc2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC

InChI Key InChIKey=HVNJSMJGJDSBBV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50082808   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082808(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-3-[3-(4-me...)
Affinity DataKi:  0.5nMAssay Description:In vitro binding affinity against alpha-1A adrenergic receptor of human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082808(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-3-[3-(4-me...)
Affinity DataKi:  440nMAssay Description:In vitro binding affinity against Alpha-1B adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082808(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-3-[3-(4-me...)
Affinity DataKi:  640nMAssay Description:In vitro binding affinity against alpha-1D adrenergic receptor of human liver microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082808(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-3-[3-(4-me...)
Affinity DataKi:  1.00E+5nMAssay Description:Binding affinity against opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed