BDBM50082870 6-(3,4-Difluoro-phenyl)-2,4-dimethyl-1-[5-(4-phenyl-piperidin-1-yl)-pentyl]-1,6-dihydro-pyrimidine-5-carboxylic acid methyl ester::CHEMBL359421

SMILES COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(CC2)c2ccccc2)C1c1ccc(F)c(F)c1

InChI Key InChIKey=YXSIJTCCPXNLJX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082870   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082870(6-(3,4-Difluoro-phenyl)-2,4-dimethyl-1-[5-(4-pheny...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity against Alpha-1A adrenergic receptor (recombinant human receptor) using [3H]prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082870(6-(3,4-Difluoro-phenyl)-2,4-dimethyl-1-[5-(4-pheny...)
Affinity DataKi:  93nMAssay Description:Binding affinity against Alpha-1B adrenergic receptor (recombinant human receptor) using [3H]prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50082870(6-(3,4-Difluoro-phenyl)-2,4-dimethyl-1-[5-(4-pheny...)
Affinity DataKi:  220nMAssay Description:Binding affinity against Alpha-1D adrenergic receptor (recombinant human receptor) using [3H]-prazosin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed