BDBM50082891 Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2]oct-2-yl ester::CHEMBL145732

SMILES CN(C)C1C2CCC(CC2OC(C)=O)C1c1ccccc1

InChI Key InChIKey=XFWUBTOVNIICAF-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50082891   

TargetTransporter(Rattus norvegicus)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.04E+4nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  5.33E+3nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  4.77E+3nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  2.45E+3nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  4.93E+3nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  4.77E+3nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  5.54E+4nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.76E+5nMAssay Description:Selectivity for the Serotonin transporter using [3H]paroxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  535nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory potency against dopamine (DA) transporter using [3H]WIN-35428 (WIN-) binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  1.04E+4nMAssay Description:Selectivity for the norepinephrine transporter using [3H]nisoxetine binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50082891(Acetic acid 6-dimethylamino-5-phenyl-bicyclo[2.2.2...)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibitory potency against [3H]DA uptake using [3H]WIN-35428 (WIN-) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed