BDBM50082986 (2S,3R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-phenylsulfanyl-succinamide::CHEMBL145128

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@@H](Sc1ccccc1)C(=O)NO)C(C)(C)C

InChI Key InChIKey=NSRKIPODZNWSLP-BRWVUGGUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082986   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082986((2S,3R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-p...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed