BDBM50082989 (2R,3S)-2-(4-Acetylamino-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL357414

SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(NC(C)=O)cc1)C(=O)NO)C(C)(C)C

InChI Key InChIKey=WCAJZIQDOXGWAG-CEXWTWQISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082989   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082989((2R,3S)-2-(4-Acetylamino-benzenesulfonylamino)-N*4...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha-converting enzyme (TACE) in blood.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082989((2R,3S)-2-(4-Acetylamino-benzenesulfonylamino)-N*4...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of TNF(tumor necrosis factor) in human bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed