BDBM50083617 (3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-phenethyl-8-aza-bicyclo[3.2.1]octane

SMILES Fc1ccc(cc1)[C@@H]1CC2CCC(C1c1ccc(F)cc1)N2CCc1ccccc1

InChI Key InChIKey=TULWTCRECLIYGX-OBZFIXDXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083617   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083617((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-phenethyl-8-az...)
Affinity DataKi: >1.30nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083617((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-phenethyl-8-az...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083617((3R,8R)-2,3-Bis-(4-fluoro-phenyl)-8-phenethyl-8-az...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed