BDBM50083624 (3R,8R)-8-[2-(4-Fluoro-phenoxy)-ethyl]-2,3-bis-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane

SMILES Fc1ccc(OCCN2C3CCC2C([C@@H](C3)c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=NQOOVQXFRXKCNC-UOVXMBPLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083624   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083624((3R,8R)-8-[2-(4-Fluoro-phenoxy)-ethyl]-2,3-bis-(4-...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083624((3R,8R)-8-[2-(4-Fluoro-phenoxy)-ethyl]-2,3-bis-(4-...)
Affinity DataKi:  27nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083624((3R,8R)-8-[2-(4-Fluoro-phenoxy)-ethyl]-2,3-bis-(4-...)
Affinity DataKi:  928nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed