BDBM50083738 CHEMBL115378::{(R)-1-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-[(isoquinoline-1-carbonyl)-amino]-propyl}-carbamic acid benzyl ester

SMILES NC(=N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2nccc3ccccc23)NC(=O)OCc2ccccc2)C1O

InChI Key InChIKey=JCPAEYOQOCMVAW-UNFSCDGZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083738   

TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083738(CHEMBL115378 | {(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083738(CHEMBL115378 | {(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083738(CHEMBL115378 | {(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083738(CHEMBL115378 | {(R)-1-{[((S)-1-Carbamimidoyl-2-hyd...)
Affinity DataIC50:  313nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed