BDBM50083751 CHEMBL420322::Pyrazine-2-carboxylic acid ((R)-4-{[((S)-1-carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-4-phenylmethanesulfonylamino-butyl)-amide

SMILES NC(=N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCCNC(=O)c2cnccn2)NS(=O)(=O)Cc2ccccc2)C1O

InChI Key InChIKey=VXYFKTJCQBMOEF-WEAPTXNRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083751   

TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083751(CHEMBL420322 | Pyrazine-2-carboxylic acid ((R)-4-{...)
Affinity DataIC50:  673nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083751(CHEMBL420322 | Pyrazine-2-carboxylic acid ((R)-4-{...)
Affinity DataIC50:  324nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083751(CHEMBL420322 | Pyrazine-2-carboxylic acid ((R)-4-{...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083751(CHEMBL420322 | Pyrazine-2-carboxylic acid ((R)-4-{...)
Affinity DataIC50:  15nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed