BDBM50083752 CHEMBL117678::N-((R)-3-{[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-carbamoyl}-3-phenylmethanesulfonylamino-propyl)-nicotinamide

SMILES NC(=N)N1CCC[C@H](NC(=O)CNC(=O)[C@@H](CCNC(=O)c2cccnc2)NS(=O)(=O)Cc2ccccc2)C1O

InChI Key InChIKey=XCCIGJJQGVKTIO-HVUWCZLESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083752   

TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083752(CHEMBL117678 | N-((R)-3-{[((S)-1-Carbamimidoyl-2-h...)
Affinity DataIC50:  79nMAssay Description:In vitro inhibition of human Factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083752(CHEMBL117678 | N-((R)-3-{[((S)-1-Carbamimidoyl-2-h...)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of human thrombolytic protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083752(CHEMBL117678 | N-((R)-3-{[((S)-1-Carbamimidoyl-2-h...)
Affinity DataIC50:  561nMAssay Description:In vitro inhibition of human trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50083752(CHEMBL117678 | N-((R)-3-{[((S)-1-Carbamimidoyl-2-h...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibition of human Thrombin (FIIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed