BDBM50083940 4-(3-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid (0.2H2O)::CHEMBL184215::CHEMBL278763::Sacchettini_6
SMILES OC(=O)C(=O)CC(=O)c1cccc(Cl)c1
InChI Key InChIKey=OGKORXSMGAWLDU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50083940
Affinity DataIC50: 170nMAssay Description:DNTB-Coupled_Enzyme_AssayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.31E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
Affinity DataIC50: 6.96E+3nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
TargetKynurenine 3-monooxygenase(Rattus norvegicus)
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair