BDBM50084134 3-[((R)-4-Benzyl-2-hydroxymethyl-piperazin-1-yl)-(4-tert-butyl-phenyl)-methyl]-phenol::CHEMBL149795

SMILES CC(C)(C)c1ccc(cc1)C(N1CCN(Cc2ccccc2)C[C@@H]1CO)c1cccc(O)c1

InChI Key InChIKey=ANLPBQYTVZSEEV-HSLSYKTRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084134   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084134(3-[((R)-4-Benzyl-2-hydroxymethyl-piperazin-1-yl)-(...)
Affinity DataIC50:  7.98E+3nMAssay Description:In vitro inhibition of [3H]-DAMGO (Tyr-D-Ala-Gly-(Me)-Phe-Gly-ol) binding to Opioid receptor mu 1 using rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084134(3-[((R)-4-Benzyl-2-hydroxymethyl-piperazin-1-yl)-(...)
Affinity DataIC50:  2.26E+3nMAssay Description:Agonist activity of the compound was determined using electrically induced smooth muscle contraction of mouse vas deferens.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50084134(3-[((R)-4-Benzyl-2-hydroxymethyl-piperazin-1-yl)-(...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of [3H]-deltorphin binding to Opioid receptor delta 1 using rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed